The cost-effectiveness of preventing mother-to-child transmission of HIV in low- and middle-income countries: systematic review

Abstract Background Although highly effective prevention interventions exist, the epidemic of paediatric HIV continues to challenge control efforts in resource-limited settings.We reviewed the cost-effectiveness of interventions to prevent mother-to-child transmission (MTCT) of HIV in low- and middle-income Toilet Brush countries (LMICs).This artic

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PRC1 chromatin factors strengthen the consistency of neuronal cell fate specification and maintenance in C. elegans.

In the nervous system, the specific identity of a neuron is established and maintained by terminal selector transcription factors that directly activate large batteries of terminal differentiation genes and positively regulate their own expression via feedback loops.However, how this is achieved in a reliable manner despite noise in gene expression

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